If you’re comparing fully canon itachi to itachi in a situation where none of that awful shit happened and danzo wasn’t a pustule and the clan and konoha were at peace, what do you think would be some major differences on his character?

[[ I can’t think of any right off the bat without like, very, very specific context. Does “none of the awful shit” include things like meeting the battlefield, having Tenma die and Shinko retire? I know you already mean the Kurama attack doesn’t occur (because that is what gets the Uchiha blamed for it), and by extension the massacre doesn’t, but I will need specifics. 

He might be less of a pacifist if he didn’t see the battlefield, which spurned him on to try to ensure people wouldn’t kill each other. His deep protection of Sasuke would still be there, though, and he’d still very much be awful at socializing. ]]

What if Sasuke had arrived at the critical point and Orochimaru had just taken his body back then?

[[ I think I drew something for that a loooooong time ago. I probably wouldn’t like it anymore fjfjkslfk. 

But, if such a thing were to happen and Itachi came across Orochimaru parading in Sasuke’s  body, we would get to figure out if it was possible to extract Orochimaru from the host body. Itachi’s absolutely going to try. 

¯_(ツ)_/¯ ]]

what could drive Itachi to genuinely turn on Konoha?

[[ Funny you ask….

Itachi discovering that Danzo sent someone to kill Sasuke, for one. Itachi asked for one thing, and Danzo cannot even hold up his end of the bargain? Slimy old man, Itachi’ll pull out Danzo’s entrails himself. He’ll release all the information he has.

Also any situation in which Sasuke gets killed in The Leaf and Itachi can pull mental hoops to blame it on Hiruzen. Which, it’s really easy for him to sklklflksl. 

His POV is that Sasuke is not supposed to die, at all. I’m sure he doesn’t know about most near-deaths (he likely gets outcomes instead of exactly what happened), but death? Not allowed. He left Sasuke there so he could live, not die. 

Don’t get Sasuke killed. ]]