[[ From around Part 1 to 4th World war, no, or at least, definitely not as bad as Itachi had it.
Sasuke always had a home and amenities available to him. Itachi’s case is different– he is traveling with one more person, they are criminals, and they are constantly being hunted. They do not have the time to brush their teeth daily nor to carry around the tools to do so. It’s secondary to survival.
Sasuke’s always had the district, and if his Mother instilled the habit, then it would’ve stayed after she died. Sasuke was alone but learned to take care of himself.
There may have been a few periods where dental hygiene became secondary, such as the day (two days) ??? when he left the Leaf to travel to Orochimaru. Or when he left Orochimaru’s, collected Taka, and hunted down Itachi, or the period of the war. All times when his “home” was not one stable location, and he was constantly moving. But the times when Sasuke’s residence is stable, and he has the amenities to brush his teeth/enact hygiene, he will.
Adult Sasuke wouldn’t be as bad as Itachi, though. It is the future, and it’s likely he can carry around a little more to take care of himself while he’s traveling and finding out info about the Otsutsuki. ]]